Your play needs to adjust accordingly when you face different opponents. When you are in a large multi-way pot, you will need to play differently than you would against a single player in a heads up situation. For one, you should play more true to the textbook in a large, multi-player pot. This means less fancy stuff: no bluffing or slow playing.
You will still get the opportunity to play more hands than normal here due to the increased implied poker odds that are created. With more players involved in the hand, there is a larger pot created, meaning that you can play hands that have higher odds. For example, if you have a flush draw with a supposed 3:1 chance of winning the hand, if there in only one other person in the hand, your implied odds will be a bit worse than 1:1. You have no business in playing this hand to the end unless you think a bluff will scare your opponent away. Now consider a larger pot, where there are five others in the hand. Your implied odds will be about 5:1, so an overlay is created where the payoff is higher than the odds are of you actually hitting your hand. Your 3:1 flush draw then becomes a good hand to see through to the last round of betting. You will win once out of every four times you play the hand, but that one time that you do win, you will win six times your original bet, creating a profit for you over the long run.